Dr. Heidi Hoffmann, Executive Director, CMC and Supply Chain at Sutro Biopharma, has 26 years of experience in biotechnology, specializing in process development, technology transfer, and manufacturing of vaccines and biological therapeutics. Directly after receiving her Ph.D. from University of California, Berkeley, Dr. Hoffmann began her career at Aviron, where she worked on process development and production of vaccines for EBV, PIV, and influenza (FluMist). She then joined Valentis, where she led the team responsible for process development, technology transfer, and clinical production of plasmid DNA for gene therapy. In 2002, Dr. Hoffmann returned to vaccine work by joining VaxGen, where she was responsible for process development and manufacturing of anthrax vaccine. Later, she transitioned into a technology transfer role, hiring and leading the VaxGen oversight team for the successful transfer of commercial production of Bristol-Meyer Squibb’s Orencia (abatacept) into the Celltrion manufacturing facility in South Korea. After the completion of that project, Dr. Hoffmann joined non-profit Global Solutions for Infectious Diseases (GSID) as Project Director responsible for coordinating the outsourcing of process development and manufacture of HIV vaccines. Dr. Hoffmann joined Sutro in February 2011 and currently heads CMC and directs outsourced cGMP manufacturing for protein therapeutics and ADCs produced using Sutro’s proprietary cell-free protein expression system
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